Pharmacologist Jobs

Job Title: In Vivo Pharmacologist Company: The Judge Group Location: Exton, PA Description: Supports in vivo disease models to evaluate biological therapeutics. Participates in small animal surgery, tumor implantation, iv. and i.p. injections, bleeds (tail vein and orbital), biopsies and autopsies. Establishes cell cultures from tumor specimens; cell cultures, cell passage, expansion and banking. Runs IVIS imaging systems. Maintains notebooks, technical reports, master logs, and lab equipment logs. Strong skills in mammalian tissue culture, vector transduction and small animal handling required; experience in imaging-related technology or IHC is a plus. Education/Experience: B.S./M.S. in Biology, Animal Science, or related field with Minimum 2 years in biotech/pharmaceutical industry LOCAL Candidates Only MUST be authorized to work in the US for any employer For complete details and consideration, please email resume to: Register to View Learn more about The Judge GroupView all of our career OpportunitiesVisit us online at www.judge.comSend this Job to a Friend

Job Title: Oncology Pharmacologist BS/MS Scientist Company: Novartis Corporation Location: Cambridge, MA Description: The successful candidate will join a dynamic, multi-disciplinary team of scientists in the In Vivo Pharmacology Oncology Group, playing a key role in the development of in vivo models of cancer and the use of those models for evaluating new drug candidates. Ideal applicants will possess excellent communication and organizational skills, critical problem-solving abilities, and a commitment to excellence.Candidate will be responsible for: Design, develop, characterize, implement and validate relevant in vivo oncology-related models including subcutaneous and orthotopic models for profiling the pharmacological effects of drug candidates Carry out ex vivo pharmaco-dynamic studies tailored to the molecular target of interest Documentation, analysis and interpretation of experiments for the evaluation of pre-clinical candidates Present results within a multidisciplinary team environmentMinimum requirementsB.A/B.S. or technical equivalent with expertise in in vivo physiology or pharmacology. Industry experience with oncology models is strongly preferred. Individuals with experience in molecular biology techniques are strongly encouraged to apply.Candidates will be expected to possess: Hands on in vivo skills necessary to validate and implement rodent oncology models including dosing and tumor implantation techniques. Experience with models derived from primary patient samples a plus. Demonstrated ability to quickly learn and perform in new areas, implement new techniques and instrumentation. Meticulous laboratory approach, careful adherence to protocol and excellent lab notebook documentation Strong analytical and computer skills Strong oral and written communication skills Demonstrated team player.

Job Title: RESEARCH PHARMACOLOGIST Company: Abbott Location: Chicago, IL Description: RESEARCH PHARMACOLOGISTAutoReqId 76399BRJob Family ScientistsJob Category Full-TimeJob Classification Experienced/EstablishedDivision Global Pharmaceutical R and DShift FirstOverview At Abbott, we provide the perspectives and experience necessary to translate science into real solutions for patients in over 130 markets worldwide. Today, 72,000 Abbott employees are doing work that matters.Job Description PRIMARY FUNCTION / MAJOR RESPONSIBILITIES:Prepares scientific reports and presentations using available software and templates.Reviews clinical protocols.Brings together all necessary data and information to prepare scientific reports; keep multiple reports moving forward simultaneously (multi-tasking).Serves as a focal point of communications among report authors and between report authors and reviewers.Complies with procedures set forth in:Departmental GuidelinesRelevant IQS documentsStudy protocolsOther directives issued by the management regarding clinical/ preclinical studies.Ensures scientific integrity of all processes.Applies the most current electronic document conventions and processes consistently and accurately.Provides PK/PD information to internal peers and department management.Committed to producing work of the highest qualityPays close attention to detailSUPERVISORY RESPONSIBILITIES:May mentor departmental personnel.ACCOUNTABILITY / SCOPE:Receives assignments from department PhD, director/associate director and is responsible for completing PK/PD objectives on schedule and largely unsupervised with consultation of Sr. Associate Pharmacokineticist and/or PhD pharmacokineticist.Uses resources appropriately and effectively to complete tasks and meet required timelines. Maximizes individual, department and team productivityReviews key decisions impacting project timelines with department management.PROBLEM SOLVING:Integrates data across studies and identifies issues impacting multiple projects.Recognizes and resolves scientific and technical problems.Independently applies expertise and experience to analyze PK, PD, and statistical data using available software.Participates on teams for process improvement initiatives.Level of opportunity commensurate with experience.Skills/Experience Requirements Basic Qualifications:Understanding of pharmacokinetic and pharmacodynamic principlesPossesses good oral and written communication skillsProficient in using computer to analyze PK/PD data, generate reports and create presentations, posters and manuscriptsKnowledge of complex scientific analyses, business-related procedures, and project leadership.Experience supporting PK/PD in clinical research, drug development and/or department operations. Proven record of successful projects.Preferred Qualifications:Education Requirements Bachelors/Masters degree, in science related to field.Significant Work Activities & Conditions Continuous sitting for prolonged periods (more than 2 consecutive hours in an 8 hour day)Percent of Travel No travelingCountry USAState/Province IllinoisSite Location Lake County,ILEmployer of Choice Through numerous local, national and international accolades, Abbott is regarded as an employer of choice for our commitment to workplace excellence. Our employees are given the tools to succeed, lead and grow, with challenging opportunities and work that makes a difference. Through our diverse healthcare businesses, we connect people and potential in ways that no other company can.Discover a world of opportunities at Abbott.EEO Statement:At Abbott, we believe that diversity drives innovation. Innovative thinkers who are passionate about the work they do, Abbott employees are representative of the diversity of the patients we strive to serve every single day across the globe.

Job Title: Senior Clinical Pharmacologist Company: Vertex Pharmaceuticals Location: Cambridge, MA Description: The Senior Clinical Pharmacologist responsibilities include assisting the planning and execution of the Clinical Development Plan for NCE(s) particularly as it applies to the discipline of Clinical Pharmacology. Can conduct, mentor and QC non-compartmental pharmacokinetic analyses. Duties may include setting or influencing the scientific directions for cross-functional team members and other members of the department. The Senior Clinical Pharmacologist will optimize interdisciplinary understanding and synergy within the Group(s) and integrate activities with those of other Departments and Teams to help shape cohesive development plans. These duties may include leading teams and independently initiating and carrying out necessary tasks to accomplish Vertex goals.Key Responsibilities* Responsible for operational leadership within the clinical pharmacology department and within the company's matrix for drug development* Oversees and can conduct the analysis, design, and interpretation of clinical pharmacology and biopharmaceutic non-compartmental studies from phase 1-4 development* Leads preparation of lucid scientific reports for all other branches and levels of the organization and its collaborators, presents expertly when called upon, and develops abilities of others in this role* Helps define scientific direction and champions technological innovation in the teams and dept* Provides strategic operational leadership to the development teams* Effectively interacts with peers, subordinates and Senior Research & Development management to move projects forward* Helps direct effective, timely and ethical publication and patenting activities for the group* Oversees effective management of Group(s)' CRO contracts and/or external communications from the Group(s)* Communicates company objectives to teams and company resource availability in a timely fashion, and develops ability of others in this role* Will supervise other Clinical Pharmacology staff, with all incumbent supervisory responsibilities

Job Title: Pharmacologist Company: Concert Pharmaceuticals Location: Lexington, MA Description: We are looking for a highly accomplished pharmacologist who has a strong background in biology and pharmacology of neurobiology/CNS disease, oncology, and/or metabolic diseases. The incumbent will be responsible for the evaluation, design, implementation and oversight of various biological assays and animal disease models. This individual will be expected to provide scientific expertise in the areas of biology and pharmacology to cross-functional preclinical drug discovery teams, as well as interact with external consultants, collaborators, and contract research organizations (CRO). The title will be determined based on the level of experience. - Provide biology and pharmacology expertise and perspective to various pre-clinical development projects across multiple therapeutic areas - Evaluate, design, develop and implement various in vitro biological assays (in-house or through external CROs) - Evaluate, design, implement and oversee in vivo pharmacology models (through external collaborators or CROs) - Work closely with internal R&D, Clinical, Regulatory, and Business Development functions in the evaluation of new product concepts - Identify and actively manage collaborations with key external experts, consultants, and CROs - Keep abreast of latest scientific advancement in the areas of biology and pharmacology of the responsible projects - Understand and apply DMPK concepts to establish PK/PD relationships and develop biomarkers - Support company goals and objectives, policies and procedures. Qualifications: Doctorate Degree in Pharmacology (or equivalent) and a minimum of 5 years experience in bio-pharmaceutical companies, with a proven record of peer-reviewed publications and project advancement. Must have solid background and extensive experience in neurobiology/CNS disease, oncology, and/or metabolic diseases. Must possess strong in vivo pharmacology expertise and project management experience with regard to preclinical development plans and design. Must have a strong technical understanding of biochemical pathways, biological processes as well as the pathophysiology of disease states. Strategic leadership experience is highly desired in addition to extensive experience in the management of external collaborations and CROs. Must be highly motivated, flexible and a strong team player able to excel in a dynamic matrix environment. Strong communication, interpersonal, and organizational skills are essential.

Job Title: Pharmacologist Company: Aerotek Location: Wilmington, DE Description: BA / BS or MS in biology, pharmacology, or related field Several years of laboratory research experience, with industry and laboratory animal experience being highly desirable CANCER EXPERIENCE VERY HIGHLY DESIREABLE Description: The candidate will join the Pharmacology group to be part of a productive motivated team supporting the successful development of small molecule therapeutics for the treatment of cancer. This scientist will perform experiments in established disease models, as well as participate in the development of novel models relevant to improving the lives of cancer patients. Experience in small animal handling is required and with in vivo tumor modeling is preferred. Familiarity with aseptic techniques, such as tissue culture and small animal surgical experience are requested. Duties: Execute in vivo disease models to evaluate small molecules for the treatment of cancer. Technical procedures include, but are not limited to: small animal dosing (IV, IP, Oral, SC, and infusion), blood collection, tissue harvesting, tumor implantation, minor animal surgery, tissue culture, and ex vivo analyses.

Job Title: Pharmacologist/Physician Company: Location: Philadelphia, PA Description: Consultant position for pharmacologist or physician who has experience wth clinical pharmacy trials and FDA approval. Please forward resume with e-mail and telephone number. You will be contacted.

Job Title: Pharmacologist/Toxicologist Company: Mylan Technologies Inc. Location: Morgantown, WV Description: Incumbent will be responsible for assisting in all facets of the Global Pharmacology and Toxicology Department. Primarily this will include managing and/or working on interdepartmental developmental project teams, but will also include direct support of Mylan Technologies' Skin Biology Laboratory. ESSENTIAL DUTIES AND RESPONSIBILITIES 1. Provide technical expertise and experience and serve as a resource to the organization. 2. Assist in the management of preclinical portions of complex applications for marketing authorizations from early development through submission, approval and post-marketing activities. 3. Assist in the development of budget, timelines, milestones for pre-clinical pharmacology and toxicology studies. This will include designing, planning and oversight of pharmacology, safety pharmacology, and toxicology studies. 4. Represent the department and Mylan in meetings with global regulatory health authorities. 5. Assist in the review and assessment of potential in-licensing opportunities for Mylan. 6. Provide support in the research and construction of regulatory study documents, technical scientific analyses and positional papers (i.e., IND/NDA documents etc.). 7. Efficiently deal with impurity, degradant, and device-related qualification issues. 8. Support generic drug development, manufacturing and distribution 9. Support of Mylan's Skin Biology Laboratory a. Coordinate product development activities with functional directors at Mylan Technologies as appropriate. b. Develop and design experiments, interpret data and produce oral and written presentation of results including final study reports c. Operating analytical equipment, such as HPLC's, to analyze test samples. d. Conduct sample processing. This includes: Understanding and following scientific procedures; operating automated instrumentation to process samples; and properly completing documentation for each analytical test e. Assist in guiding and training new hires in work-related functions. f. Assist in the development and validation of new methodology, including but not limited to, reading, analyzing, and interpreting professional journals, technical procedures, or government regulations, to evaluate applicability. g. Review data and documentation prior to report generation and make presentation to management. This review includes qualitative review of chromatography/spectra; and interpretation of data according to Standard Operating Procedures h. Assists with the installation and maintenance of equipment and facilities necessary to conduct evaluations of transdermal product formulations. 10. Assist in maintaining Mylan's Toxicology, Biological and Nonclinical Specimen Archives. 11. Review for comprehension relevant Mylan Standard Operational Procedures (SOPs) and ensure compliance with Laboratory SOPs and other relevant policies. 12. Ensure data quality and integrity from Mylan sponsored studies. 13. Review for comprehension relevant Mylan Standard Operational Procedures (SOPs) and ensure compliance with Laboratory SOPs and other relevant policies. 14. Assist in the direction of laboratory and administrative employees. Carries out supervisory responsibilities in accordance with the organization's policies and applicable laws. Reporting Structure:

Job Title: Cardiovascular Safety Pharmacologist, DSRD Global Safety Pharmacology Company: PfizerInc. Location: Groton, CT Description: This is your opportunity to join Pfizer R&Dyy s Global Safety Pharmacology department and contribute to our success in delivering new medicines from bench to bedside. In this role you will: - Partner globally with R&D scientists and clinicians to shape new and important drug developments from initial discovery through to product launch - Join a recognized industry leader in Safety Pharmacology - Thrive in an environment that actively promotes scientific publishing - Work to high standards including Good Laboratory Practice (GLP) generating high quality data and solving complex safety problems - Play a part in leading the discipline forward - Interface with key external regulatory and scientific stakeholders We are looking for a highly skilled scientist to join the Cardiovascular (CV) Discipline to add to the scientific leadership in this area and meet the demand for the development of new, and the application of established, models of CV function. The position involves working both individually and as part of a team to support early and late stage projects in the risk management of CV issues. This includes the direct interaction with project teams and the design, conduct and interpretation of experiments to assess the CV safety of putative new medicines in support of both drug discovery as well as regulatory requirements. The role offers the chance to work across the whole Pfizer portfolio and is one of high responsibility and impact in drug discovery and development. The role requires innovative thinking to look for new opportunities such as the application of novel PKPD protocol designs and the incorporation of safety pharmacology endpoints in toxicology studies. As part of a global team you will have a network of partners at other sites that you will work with to share learning and develop our expertise and ability to manage this key safety issue. It is expected that you will contribute to the development of the CV discipline strategy, potentially running global initiatives in support of this. This position requires independent scientific thinking, trouble-shooting skills, and good judgment as actions are expected to impact departmental, site and global goals.EDUCATIONAL BACKGROUND: A BSc, with several years experience working in the CV area, possibly with a MSc or a Ph.D. in pharmacology, physiology or a related biological discipline. WORK EXPERIENCE: Ideally industry experience working in drug safety or discovery. Alternatively post-doc experience in CV pharmacology or physiology REQUIRED: Experience of performing, interpreting and communicating CV safety studies in laboratory species. Experience of integrating large data sets to develop an understanding of the issue and the associated risk e.g. hERG, WLP, in vivo to clinic. Experience of working with project teams as a safety pharmacologist and/or DSTL. Evidence of scientific leadership. Good communication skills, diligence and personal leadership skills are also required OTHER ATTRIBUTES DESIRABLE: Experienced in the reading of NHP ECGs. Experience of working in a multidisciplinary drug safety department with a broader perspective of drug safety.RJC:1066

Job Title: Animal Pharmacologist Company: Chromocell Location: North Brunswick, NJ Description: Chromocell is a life sciences company located in North Brunswick, NJ. We work on the most challenging and previously inaccessible targets to identify novel therapeutic compounds. We have developed a unique drug discovery platform allowing us to discover and develop drugs for some of the most important but so far elusive therapeutic areas dealing with pain and CNS indications like PTSD, anxiety, depression, sleep and memory. This platform has also been found to be useful when working with respiratory indications such as Cystic Fibrosis and COPD. Our exciting and promising leads in these and other areas are currently progressing through development including animal studies. We are expanding our capabilities with a number of key individuals including an Animal Pharmacologist. Chromocell seeks highly talented and motivated people excited by the challenges of technology development and novel approaches to drug discovery. Team members are active individual contributors who also function well in a closely-meshed and fast-paced team environment. All candidates must have excellent oral, written and computer communication skills; the ability to perform efficiently and organize priorities in response to firm timelines is essential. .